Structure – Function Relationships of Pre-Fibrillar Protein Assemblies in Alzheimers Disease and Related Disorders
نویسندگان
چکیده
منابع مشابه
Structure-function relationships of pre-fibrillar protein assemblies in Alzheimer's disease and related disorders.
Several neurodegenerative diseases, including Alzheimer's, Parkinson's, Huntington's and prion diseases, are characterized pathognomonically by the presence of intra- and/or extracellular lesions containing proteinaceous aggregates, and by extensive neuronal loss in selective brain regions. Related non-neuropathic systemic diseases, e.g., light-chain and senile systemic amyloidoses, and other o...
متن کاملMethods for Studying and Structure–Function Relationships of Non-Fibrillar Protein Assemblies in Alzheimer's Disease and Related Disorders
Several neurodegenerative diseases, including Alzheimer's, Parkinson's, Huntington's, and prion diseases, are characterized by intraand/or extracellular deposition of fibrillar proteinaceous aggregates, and by extensive, neuron loss. Related non-neuropathic systemic diseases, e.g., light-chain and senile systemic amyloidoses, and other organ-specific diseases, such as dialysis-related amyloidos...
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translation as a comunicative process is always said to be associated with various aspects of meaning loss or gain. subtitling as a mode of translating, due to special discoursal and textual conditions imposed upon it, is believed to be an obvious case of this loss or gain. presenting the spoken sound track of a film in writing and synchronizing the perception of this text by the viewers with...
15 صفحه اولGlucoamylase: structure/function relationships, and protein engineering.
Glucoamylases are inverting exo-acting starch hydrolases releasing beta-glucose from the non-reducing ends of starch and related substrates. The majority of glucoamylases are multidomain enzymes consisting of a catalytic domain connected to a starch-binding domain by an O-glycosylated linker region. Three-dimensional structures have been determined of free and inhibitor complexed glucoamylases ...
متن کاملEffect of topiramate on apoptosis-related protein expression of hippocampus in model rats with Alzheimers disease.
OBJECTIVES Alzheimer's disease is an age-related neurodegenerative disease and a synaptic function defect disease, the clinical symptoms are mainly progressive cognitive impairment, affecting patient's social function. Aim of this report was to investigate the effect of topiramate on apoptosis-related protein expression (Bcl-2, Survivin, Fas, Bax and Caspase-3) in the hippocampus of a rat model...
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ژورنال
عنوان ژورنال: Current Alzheimer Research
سال: 2008
ISSN: 1567-2050
DOI: 10.2174/156720508784533358